Nucleotides: 745GT>AG deletion-insertion;

Amino acids: V249R;

Hybrid allele encompassing at least one RHCE exon: no

Comments on the molecular basis:

Extracellular position of one or more amino acid substitutions:

• none of the mutations are predicted to affect an extracellular amino acid

Splicing:

Unconventional prediction methods:

Reports by D phenotype

Other RH phenotypes: RH:

Serology with monoclonal anti-D

Antigen Density (Ag/RBC)

More phenotype data

Reports by CcEe phenotype

Reports by allele association

Antibodies in D negative recipients

Alloimmunization in recipients: expected to be possible, see phenotype data

Detailed reports

• 1/136000 among about 136.000 donors with D negative phenotype, systematically tested for the presence of the RHD gene; the RHD gene was detected in 300 donors in the German population (some samples may overlap with other studies)

Allele or phenotype frequency