RHD*541T
(ISBT table: not listed)
				This entry is an RHD allele.
						D541T, RHD(L181L), RHD*541C>T, RHD*541T, 
					
	
				Molecular data
						Nucleotides:
						541C>T; 
					
Amino acids: L181L;
						Hybrid allele encompassing at least one  RHCE  exon:
						no
					
						Comments on the molecular basis:
						
						Extracellular position of one or more amino acid substitutions: 
						
- Silent or intronic mutations: none of the mutations are predicted to affect an extracellular amino acid.
 
						Splicing:
						
						Unconventional prediction methods:
						
Phenotype
Main D phenotype: unknown (last update: Nov. 17, 2019)Reports by D phenotype
Other RH phenotypes: RH:
Serology with monoclonal anti-D
Antigen Density (Ag/RBC)
More phenotype data
Rhesus Similarity Index
Haplotype
Main CcEe phenotype association: ce (last update: Jan. 8, 2021)Alloimmunization
Antibodies in carriers
Antibody specificity: D (RH1)
Summary: no published cases (last update: Nov. 17, 2019)Detailed information
Antibodies in D negative recipients
Alloimmunization in recipients: unknown
Reports
Summary: exceptional description(s), in African Americans (last update: Dec. 22, 2019)Structure mapping
| Movement | Mouse Input | Touch Input | ||
|---|---|---|---|---|
| Rotation | Primary Mouse Button | Single touch | ||
| Translation | Middle Mouse Button or Ctrl+Primary | Triple touch | ||
| Zoom | Scroll Wheel or Second Mouse Button or Shift+Primary | Pinch (double touch) | ||
| Slab | Ctrl+Second | Not Available | 
References
- Reid ME et al. Genomic analyses of RH alleles to improve transfusion therapy in patients with sickle cell disease. Blood Cells Mol Dis, 2014. [Citation] [RHeference]
 - Floch A et al. Comment from Rheference Online ressource, 2020. — Online ressource — [RHeference]
 - Stef M et al. RH genotyping by nonspecific quantitative next-generation sequencing. Transfusion, 2020. [Citation] [RHeference]
 
Last update: Jan. 8, 2021