partly characterized RHD*10 (DAU) (partly characterized or subtypes not separated)
(ISBT table: not listed)
This entry is partly characterized.
RHD*DAU - partly characterized or subtypes not separated,
Phenotype
Main D phenotype: NA (last update: Aug. 30, 2020)Reports by D phenotype
Other RH phenotypes: RH:
Serology with monoclonal anti-D
Antigen Density (Ag/RBC)
More phenotype data
Rhesus Similarity Index
Haplotype
Main CcEe phenotype association: NA (last update: Jan. 1, 2020)ce | Ce | cE | CE | |
---|---|---|---|---|
ce | 0 | 0 | 0 | 0 |
Ce | 0 | 0 | 0 | |
cE | 0 | 0 | ||
CE | 0 |
Reports by CcEe phenotype
Reports by allele association
Alloimmunization
Antibodies in carriers
Antibody specificity: D (RH1)
Summary: not relevant, see types or alleles (last update: Aug. 25, 2020)Detailed information
-
Daniels G et al. Br J Haematol (2013)
(review; Table I)
- Ab specificity: D (RH1)
- Number (auto- or allo-):
- Number listed as allo-: no new case detailed (listed as alloanti-D)
- Number listed as auto-: NA
- Number of carriers of the allele assessed: NA
- DAT: NA
- Autologuous control: NA
- Elution: NA
- Autoadsorption: NA
- Titer: NA
- Was anti-LW excluded?: NA
- Other antibodies detected: NA
- Cross matches (with Ab and RBCs from different partial types): NA
- Transfusion history: NA
- Pregnancy history:
- Anti-D Ig history: NA
- Context: NA
- Hemolytic consequences: NA
- Comment: list of D variants associated with alloanti-D formation
Antibodies in D negative recipients
Alloimmunization in recipients: expected to be possible, see phenotype data
Reports
Summary: NA, NA (last update: Aug. 25, 2020)Detailed reports
- 2/430 (1 heterozygous) among samples with ambigous D phenotype in the French population (Table S1)
- 4/627 weak D typing (95% from patients, 5% from donors; 21,2% were identified as RHef00442 or RHef00446 by authors, "mostly (…) inconclusive serology consequent to recent transfusion") in the Belgian (Flanders) population
- 75/2257 (34 RHef00634, 28 RHef00008 or RHef00013 or RHef00017 or RHef00018, 8 RHef00019 or RHef00020, 5 compound heterozygous: 2 RHef00008 / RHef00020, 1 RHef00634 / RHef00602, 1 RHef00008 / RHef00321, 1 RHef00020 / RHef00442) among samples referred to the regional reference laboratory United States (Wisconsin)
- 22/3147 (1 RHef00634, 3 RHef00008, 4 RHef00017, 2 RHef00019, 1 RHef00022, 11 compound heterozugous: 5 RHef00008 / RHef00442, 1 RHef00008 / RHef00447, 1 RHef00008 / RHef00452, 1 RHef00011 / RHef00447, 1 RHef00018 / RHef00442, 1 RHef00018 / RHef00602, 1 RHef00018 / RHef00452) among samples referred to the regional reference laboratory Germany (Lower Saxony)
- 7/1271 (2 RHef00634, 3 RHef00019 or RHef00020, 2 RHef00022) among samples referred to the regional reference laboratory Upper Austria
Allele or phenotype frequency
Structure mapping
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References
- Wagner FF et al. The DAU allele cluster of the RHD gene. Blood, 2002. [Citation] [RHeference]
- Daniels G et al. Variants of RhD--current testing and clinical consequences. Br J Haematol, 2013. [Citation] [RHeference]
- Fichou Y et al. Establishment of a medium-throughput approach for the genotyping of RHD variants and report of nine novel rare alleles. Transfusion, 2013. [Citation] [RHeference]
- Van Sandt VS et al. RHD variants in Flanders, Belgium. Transfusion, 2015. [Citation] [RHeference]
- Srivastava K et al. The DAU cluster: a comparative analysis of 18 RHD alleles, some forming partial D antigens. Transfusion, 2016. [Citation] [RHeference]
- Floch A et al. Comment from Rheference Online ressource, 2020. — Online ressource — [RHeference]
Last update: Jan. 15, 2021