RHD*149A
(ISBT table: not listed)
This entry is an RHD allele.
RHD(V50D), RHD*149A, RHD*149T>A,
Molecular data
Nucleotides:
149T>A;
Amino acids: V50D;
Hybrid allele encompassing at least one RHCE exon:
no
Comments on the molecular basis:
Extracellular position of one or more amino acid substitutions:
- considered to be extracellular
- none of the mutations are predicted to affect an extracellular amino acid
Splicing:
Unconventional prediction methods:
Phenotype
Main D phenotype: weak D (last update: Nov. 17, 2019)Reports by D phenotype
Other RH phenotypes: RH:
Serology with monoclonal anti-D
Antigen Density (Ag/RBC)
More phenotype data
Rhesus Similarity Index
Haplotype
Main CcEe phenotype association: unknown (last update: Dec. 9, 2020)Alloimmunization
Antibodies in carriers
Antibody specificity: D (RH1)
Summary: no published cases (last update: Nov. 17, 2019)Detailed information
Antibodies in D negative recipients
Alloimmunization in recipients: expected to be possible, see phenotype data
Reports
Summary: exceptional description(s), in the French population (last update: Dec. 22, 2019)Structure mapping
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| Zoom | Scroll Wheel or Second Mouse Button or Shift+Primary | Pinch (double touch) | ||
| Slab | Ctrl+Second | Not Available |
References
- Floch A et al. Molecular characterization of 13 new RHD alleles. Transfusion, 2017. [Citation] [RHeference]
- Floch A et al. Comment from Rheference Online ressource, 2020. — Online ressource — [RHeference]
Last update: Oct. 4, 2019